• Mohapatra S.#, Chakraborty T. #, Reza M.A.N., Shimizu S., Matsubara T., Ohta K. Short-term starvation and realimentation helps stave off Edwardsiella tarda infection in red sea bream (Pagrus major). Comparative Biochemistry and Physiology: Part B. 206: 42-53. [# Authors contributed equally]. (2017).
  • Chakraborty T. #, Mohapatra S. #, Tobayama M. #, Ohta K., Ryu Y.W., Kazeto Y., Ohta K., Zhou L.Y., Nagahama Y., Matsubara T. Hatching enzymes disrupt aberrant gonadal degeneration by the autophagy/apoptosis cell fate decision. Scientific Reports. 7: 3183. [# Authors contributed equally]. (2017).
  • Pandey, D. , Ryu, Y.W. , and Matsubara, T. Features of Sperm Motility and Circadian Rhythm in Japanese Anchovy (Engraulis japonicus). Fisheries and Aquaculture Journal, DOI: 10.4172/2150-3508. 10000203. (2017).
  • Pandey, D. , Ryu, Y.W. , Goto, R., and Matsubara, T. Morphological and biochemical changes in oocytes during final oocyte maturation in Japanese anchovy (Engraulis japonicus). Aquacult.Sci, 65(1), 29-40. (2017).
  • Golpour, A., Broquard, C., Milla, C., Dadras, H., Baloch, A.R., Saito, T., Pšenička, M. Gonad histology and serum 11-KT profile during the annual reproductive cycle in sterlet sturgeon adult males, Acipenser ruthenus. Reproduction in Domestic Animals, DOI: 10.1111/rda.12911. (2017).
  • Fujimoto, T., Yamada, A., Kudo, Y., Nakaya, K., Okubo- Murata, M., Saito, T., Ninomiya, K., Inaba, M., Kuroda, M., Arai, K., Murakami, M. Development of nuclear DNA markers to characterize genetically diverse groups of Misgurnus anguillicaudatus and its closely related species. Fisheries Science, Accepted. (2017).


  • Zhou L.Y., Luo F., Fang X., Charkraborty T., Wu L., Wei J., Wang D.S. Blockage of Progestin physiology disrupts ovarian differentiation in XX Nile tilapia (Oreochromis niloticus). Biochemical and Biophysical Research Communications. 473(1):29-34. (2016).
  • Mohapatra S. #, Chakraborty T. #, Kacem R.H., Shimizu S., Matsubara T., Ohta K. Starvation: An Alternate Measure to Improve Immunity and Physiology of Red Sea Bream during Edwardsiella tarda Infection. Journal of Aquatic Research and Development S2:007. [# Authors contributed equally]. (2016).
  • Zhao, Y., Fujimoto, T., Pšenička, M., Saito, T., Arai, K. Non-motile tetraploid spermatozoa of Misgurnus loach hybrids. Fisheries Science, 82(1), pp 127-135. (2016).
  • Pšenička, M., Saito, T., Rodina, M., Dzyuba, B. Cryopreservation of early stages of germ cells in sturgeon, comparison between whole tissue and dissociated cells freezing. Cryobiology, doi:10.1016/j.cryobiol.2016.02.005 (2016).
  • Robles, V., Riesco, MF., Psenicka, M., Saito, T., Valcarce, DG., Cabrita, E., Herráez, P. Biology of teleost primordial germ cells (PGCs) and spermatogonia: biotechnological applications. Aquaculture, doi:10.1016/j.aquaculture.2016.03.004 (2016).
  • Güralp, H., Pocherniaieva, K., Blecha, M., Policar, T., Pšenička, M., Saito, T. Early embryonic development in pikeperch (Sander lucioperca) related to micromanipulation. Czech Journal of Animal Science 61(06):273-280 (2016).
  • Güralp, H., Pocherniaieva, K., Blecha, M., Policar, T., Pšenička, M., Saito, T. The migration of primordial germ cells during late embryogenesis of pikeperch Sander lucioperca relative to blastomere transplantation Czech Journal of Animal Science, Accepted. (2016).
  • Zhou, L., Charkraborty, T., Zhou, Q., Mohapatra, S., Nagahama, Y. and Zhang, Y. Rspo1-activated signalling molecules are sufficient to induce ovarian differentiation in XY medaka (Oryzias latipes). Sci. Rep. 6: 19543 (2016).
  • Zhang, X., Guan, G., Li, M., Zhu, F., Liu, Q., Naruse, K, Herpin, A., Nagahama, Y., Li, J. and Hong, Y. Autosomal gsdf acts as a male sex initiator in the fish medaka. Sci. Rep. 6: 19738 (2016).
  • Chakraborty, T., Zhou, L.Y., Chaudhari, A., Iguchi, T. and Nagahama, Y. Dmy initiates masculinity by altering Gsdf/Sox9a2/Rspo1 expression in medaka (Oryzias latipes). Sci. Rep. 6: 19480 (2016).


  • Qiu Y.#, Sun S.#, Chakraborty T.#, Wu L., Sun L., Wei J., Nagahama Y., Wang D. S., Zhou L. Y. Figla favors ovarian differentiation in a teleosts, Nile tilapia (Oreochromis niloticus). Plos One. 10(4): e0123900 [# Authors contributed equally]. (2015).
  • Tzung, KW., Goto, R., Saju, JM., Sreenivasan, R., Saito, T., Arai, K., Yamaha, E., Hossain, MS., Calvert, ME., and Orbán, L. Early Depletion of Primordial Germ Cells in Zebrafish Promotes Testis Formation. Stem cell reports, 4(1), 61-73. (IF 2015 = 5.365) (2015).
  • Pšenička, M., Saito, T., Linhartová, Z., & Gazo, I. Isolation and transplantation of sturgeon early-stage germ cells. Theriogenology, 83(6), 1085-1092. (IF 2014 = 1.845) (2015).
  • Saito, T., Pšenička, M. Novel technique for visualizing primordial germ cells in sturgeons (Acipenser ruthenus, A. gueldenstaedtii, A. baerii, and Huso huso). Biology or Reproduction, 93(4), 1-7. (2015).
  • Linhartova, Z., Saito, T., and M. Psenicka. Sterilization of sterlet Acipenser ruthenus by using knock down agent, antisense morpholino oligonucleotide, against dead end. Theriogenology, 84(7), 1246-1255. (2015).
  • Hou, J., Fujimoto, T., Saito, T., Yamaha, E., and Arai, K. Generation of clonal zebrafish line by androgenesis without egg irradiation. Scientific Reports, 5:13346. (IF 2015 = 5.578) (2015).
  • Goto R, Saito T, Kawakami Y, Kitauchi T, Takagi M, Todo T, Arai K, and Yamaha E. Visualization of primordial germ cells in the fertilized pelagic eggs of the barfin flounder Verasper moseri. International Journal of Developmental Biology, 59(10-12), 465-470. (2015).
  • Senthilkumaran, B., Sreenivasulu, G., Wang, D.S., Sudhakumari, C.C., Kobayashi, T. and Nagahama, Y. Expression patterns of CREBs in oocyte growth and maturation of fish. PLos One 10: e0145182 (2015).
  • Qui, Y., Sun, S., Charkraborty, T., Sun, L., Wei, J., Nagahama, Y., Wang, D. and Zhou, L. Fig1α favors ovarian differentiation by antagonizing spermatogenesis in a teleost, Nile tilapia (Oreochromis niloticus). PloS One 10: e0123900 (2015).
  • Mohapatra, S., Chakraborty, T., Shimizu, S., Urasaki, S., Matsubara, T., Nagahama, Y. and Ohta, K. Starvation beneficially influences the liver physiology and nutrient metabolism in Edwardsiella tarda infected red sea bream (Pagrus major). Comp. Biochem. Physiol. A Mol. Integr. Physiol. 189: 1-10 (2015).


  • Yu X., Wu L., Xie L., Yang S., Chakraborty T., Shi H., Wang D. S., Zhou L. Y. Characterisation of two paralogous StAR genes in a teleost, Nile tilapia (Oreochromis niloticus). Molecular and Cellular Endocrinology. 392: 152-162. (2014).
  • Mohapatra S.#, Chakraborty T.#, Prusty A. K., Pani Prasad K., Mohanta K. N. Dietary multispecies probiotic supplementation enhances the immuno-hematological responses and reduces mortality by Aeromonas hydrophila in Labeo rohita fingerlings. Journal of World Aquaculture Society. 45(5): 532-544 [# Authors contributed equally, Corresponding author]. (2014).
  • Mohapatra S.#, Chakraborty T.#, Prusty A. K., Pani Prasad K., Mohanta K. N. Beneficial effects of dietary probiotics mixture on hemato-immunology and cell apoptosis of Labeo rohita fingerlings reared at higher water temperatures. Plos One 9(6): e100929 [# Authors contributed equally, Corresponding author]. (2014).
  • Linhartova, Z., Saito, T., and M. Psenicka. Embryogenesis, visualization and migration of primordial germ cells in tench (Tinca tinca). Journal of Applied Ichthyology 30.s1 (2014): 29-39. (IF 2012 = 0.902) (2014).
  • Zhao, Y., Saito, T., Pšenička, M., Fujimoto, T., and Arai, K. Comparison of spermatozoa parameters, fine structures, and energy-related factors among tetraploid, hyper-tetraploid, and hyper-triploid loaches (Misgurnus anguillicaudatus). Journal of Experimental Zoology Part A: Ecological Genetics and Physiology, 321(4), 198-206. (IF 2012 = 1.610) (2014).
  • Linhartova, Z., Rodina, M., Guralp, H., Gazo, I., Saito, T., and M. Psenicka. Isolation and cryopreservation of early stages of germ cells of tench (Tinca tinca). Czech Journal Of Animal Science, 59 (8): 381-390 (2014).
  • Dzyuba, B., Boryshpolets, S., Cosson, J., Dzyuba, V., Fedorov, P., Saito, T., Pšenička, M., Linhart, O., and Rodina, M. Motility and fertilization ability of sterlet Acipenser ruthenus testicular sperm after cryopreservation. Cryobiology, 69(2), 339-341. (IF 2014 =1.643) (2014).
  • Hou, J., Saito, T., Fujimoto, T., Yamaha, E. and Arai, K. Androgenetic doubled haploids induced without irradiation of eggs in loach (Misgurnus anguillicaudatus). Aquaculture. 420-421(Supplement 1): S57-S63 (IF 2012 = 2.009) (2014).
  • Saito, T., Pšenička, M., Goto, R., Adachi, S., Inoue, K., Arai, K., & Yamaha, E. The origin and migration of primordial germ cells in sturgeons. PloS One, 9(2), e86861. (IF 2012 = 3.730) (2014).
  • Guan, G., Yi, M., Kobayashi, T., Hong, Y. and Nagahama, Y. A syntenic region conserved from fish to mammalian X chromosome. Int. J. Evo. Biol. 2014, Article ID 873935, 10 pages (2014).


  • Zhao, H., Guan, G., Duan, J., Cheng, N., Wang, J., Matsuda, M., Paul-Prasanth, B. and Nagahama, Y. O14E, a eukaryotic translation initiation n factor 4E-binding protein of medaka fish (Oryzias latipes), can interact with nanos3 and vasa in vitro. J. Exp. Zool. B Mol. Dev. Evol. 320: 10-21 (2013).
  • Paul-Prasanth, B., Bhandari, R.K., Kobayashi, T., Horiguchi, R., Kobayashi, Y., Nakamoto, M., Shibata, Y., Sakai, F., Nakamura, M. and Nagahama, Y. Estrogen oversees the maintenance of the female genetic program in terminally differentiated gonochorists. Sci. Rep. 3: 2862 (2013).
  • Nakasone, K., Nagahama, Y. and Okubo, K. Hebp3, a novel member of the heme-binding protein gene family, is expressed in the medaka meninges with higher abundance in females due to a direct stimulating action of ovarian estrogens. Endocrinology 154: 920-930 (2013).
  • Kobayashi, Y., Nagahama, Y. and Nakamura, M. Diversity and Plasticity of sex determination and differentiation in fishes. Sex. Dev. 7: 115-125 (2013).
  • Horiguchi, R., Nozu, R., Hirai, T., Kobayashi, Y., Nagahama, Y. and Nakamura, Y. Characterization of gonadal soma-derived factor expression during sex change in the protogynous wrasse, Halichoeres trimaculatus. Dev. Dyn. 242: 388-399 (2013).
  • Hiraki, T., Nakasone, K., Hosono, K., Kawabata, Y., Nagahama, Y. and Okubo, K. Neuropeptide B is female-specifically expressed in the telencephalic and preoptic nuclei of the medaka brain. Endocrinology 155: 1021-1032 (2013).
  • Guan, G., Yan, Y., Chen, T., Yi, M., Ni, H., Naruse, K., Nagahama, Y. and Hong, Y. Nanos3 gene targeting in medaka ES cells. Int. J. Biol. Sci. 9: 444-454 (2013).
  • Miura, T., Miura, C., Fukushima, E., Iwai, T., Celino, F. T., Watanbe, N., Uehara, M., Ohashi, H., Yoshida, S., Hosokawa, H., Urasaki, S. Kuwayama, K. Uchimura Y., Sone, K. Odawara Y. and Ido, A. Recent research trend for the culture of pearls in uwa-sea of Ehime prefecture, Japan. Recent Advances in Pearl Research, Eds., S. Watabe, K. Maeyama and H. Nagasawa, pp. 207-229 (2013).
  • Fukushima, E., Iwai, T., Miura, C., Watanbe, N., Urasaki, S., Kuwayama, K., Odawara, K. and Miura, T. Newly-developed technique for producing pearls using mantle grafts of black-lipped pearl oyster (Pinctada margaritifera) in immunologically tolerant akoya pearl oyster (Pinctada fucata). Recent Advances in Pearl Research, Eds., S. Watabe, K. Maeyama and H. Nagasawa, pp.249-253 (2013).
  • Higuchi, M., Miura, C., Iwai, T. and Miura, T. Trypsin regulates meiotic initiation in Japanese eel (Anguilla japonica) by promoting the uptake of taurine into germ cells during spermatogenesis. Biol. Reprod. 89: 58, 1-9 (2013).


  • Mohapatra S.#, Chakraborty T.#, Prusty A. K., Kumar K., Pani Prasad K., Mohanta K. N. Fenvalerate induced stress mitigation by dietary supplementation of multispecies probiotic mixture in a tropical freshwater fish, Labeo rohita (Hamilton). Pesticide Biochemistry and Physiology. 104: 28-37 [# Authors contributed equally, Corresponding author]. (2012).
  • Zhao, Y., Psenicka, M., Fujimoto, T., Saito, T., Yasui, GS., Yamaha, E., Arai, K. Motility, morphology, mitochondria and ATP content of diploid spermatozoa from sex-reversed clonal diploid and neo-tetraploid loach, Misgurnus anguillicaudatus. Journal of Applied Ichthyology. 28, 1006–1012. (IF 2011 = 0.869) (2012).
  • Kitauchi, T., Saito, T., Motomura, T., Arai, K., Yamaha, E. Distribution and function of germ plasm in cytoplasmic fragments from centrifuged eggs of the goldfish, Carassius auratus. Journal of Applied Ichthyology. 28, 998–1005. (IF 2011 = 0.869) (2012).
  • Kawakami, Y., Saito, T., Fujimoto, T., Goto-Kazeto, R., Takahashi, E., Adachi, S., Arai, K., Yamaha, E. Technical note: viability and motility of vitrified/thawed primordial germ cell isolated from common carp (Cyprinus carpio) somite embryos. Journal of Animal Science. 90, 495-500. (IF 2011 = 2.096) (2012).
  • Kawakami, Y., Ishihara, M., Saito, T., Fujimoto, T., Adachi, S., Arai, K., and Yamaha, E. Cryopreservation of green fluorescent protein (GFP)-labeled primordial germ cells with GFP fused to the 3′ UTR of the nanos gene by vitrification of Japanese eel (Anguilla japonica) somite-stage embryos. Journal of Animal Science. (IF 2011 = 2.096) (2012).
  • Goto, R., Saito, T., Takeda, T., Fujimoto, T., Takagi, M., Arai, K., and Yamaha, E. Germ cells are not the primary factor for sexual fate determination in goldfish. Developmental Biology 370, 98–109. (IF 2011 = 4.069) (2012).
  • Zhao, H., Duan, J., Cheng, N. and Nagahama, Y. Specific expression of Olpiwi1 and Olpiwi2 in medaka (Oryzias latipes) germ cells. Biochem. Biophys. Res. Commun. 418: 592-597 (2012).
  • Lee, W., Kang, C.W., Su, C.K., Okubo, K. and Nagahama, Y. Screening estrogenic activity of environmental contaminants and water samples using a transgenic medaka embryo bioassay. Chemosphere 88: 945-952 (2012).
  • Hiraki, T., Takeuchi, A., Tsumaki, T., Zempo, B., Kanda, S., Oka, Y., Nagahama, Y. and Okubo, K. Female-specific target sites for both oestrogen and androgen in the teleost brain. Proc. Biol. Sci. (Proc. Royal Soc. B) 279 (1749); 5014-5023 (2012).
  • Zhou, L.Y., Wang, D.S., Charkraborty, T., Mohapatra, S. and Nagahama, Y. R-spondins are involved in the ovarian differentiation in a teleost, medaka (Oryzias latipes). BMC Dev. Biol. 12: 36 (2012).


  • Chakraborty T., Katsu Y., Zhou L. Y., Miyagawa S., Nagahama Y., Iguchi T. Estrogen receptors in medaka (Oryzias latipes) and estrogenic environmental contaminants: An in vitro–in vivo correlation. Journal of Steroid Biochemistry and Molecular Biology. 123:115–121. (2011).
  • Chakraborty T., Shibata Y., Zhou L. Y., Katsu Y., Iguchi T., Nagahama Y. Differential expression of three estrogen receptor subtype mRNAs in gonads and liver from embryos to adults of the medaka, Oryzias latipes. Molecular and Cellular Endocrinology. 333:47–54. (2011).
  • Saito, T., Goto-Kazeto, R., Kawakami, Y., Nomura, K., Tanaka, H., Adachi, S., Arai, K., and Yamaha, E. The mechanism for primordial germ-cell migration is conserved between Japanese eel and zebrafish. PLoS ONE 6, e24460–. (IF 2010 = 4.411) (2011).
  • Wong, T.T., Saito, T., Crodian, J., and Collodi, P. Zebrafish Germline Chimeras Produced by Transplantation of Ovarian Germ Cells into Sterile Host Larvae. Biology of Reproduction 84, 1190–1197. (IF 2010 = 3.870) (2011).
  • Kawakami, Y., Saito, T., Fujimoto, T., Goto-Kazeto, R., Takahashi, E., Adachi, S., Arai, K., and Yamaha, E. Visualization and motility of primordial germ cells using green fluorescent protein fused to 3’UTR of common carp nanos-related gene. Aquaculture 317, 245–250. (IF 2010 = 2.044) (2011).
  • Cui, J., Shen, X., Zhao, H. and Nagahama, Y. (2011). Genome-wide analysis of Sox genes in medaka (Oryzias latipes) and their expression pattern in embryonic development. Cytogenet. Genome Res. 134: 283-294 (2011).
  • Mita, M., Yamamoto, K. and Nagahama, Y. Interaction of relaxin-like gonad-stimulating substance with ovarian follicle cells of the starfish Asterina pectinifera. Zool. Sci. 28: 764-769 (2011).
  • Mita, M., Yamamoto, K., Nakamura, M. and Nagahama, Y. Hormonal action of relaxin-like gonad-stimulating substance (GSS) on starfish ovaries in growing and fully grown states. Gen. Comp. Endocrinol. 172: 85-89 (2011).
  • Okubo, K., Takeuchi, A., Chaube, R., Paul-Prasanth, B., Kanda, S., Oka, Y. and Nagahama, Y. Sex differences in aromatase gene expression in the medaka brain. J. Neuroendocrinol. 23: 412-423 (2011).
  • Fernandino, J.I., Popesku, J.T., Paul-Prasanth, B., Xiong, H., Hattori, R.S., Oura, M., Strussmann, C.A., Somoza, G.M., Matsuda, M., Nagahama, Y. and Trudeau, V.L. Analysis of sexually dimorphic expression of genes at early gonadogenesis of Pejerrey Odontesthes bonariensis uing a heterologous microarray. Sex. Dev. 5: 89-101 (2011).


  • Fujimoto, T., Saito, T., Sakao, S., Arai, K., and Yamaha, E. Developmental potential of embryonic cells in a nucleocytoplasmic hybrid formed using a goldfish haploid nucleus and loach egg cytoplasm. Int. J. Dev. Biol. 54, 827–835. (IF 2010 = 2.856) (2010).
  • Goto-Kazeto, R., Saito, T., Takagi, M., Arai, K., and Yamaha, E. Isolation of teleost primordial germ cells using flow cytometry. Int. J. Dev. Biol. 54, 1485–1490. (IF 2010 = 2.856) (2010).
  • Kawakami, Y., Goto-Kazeto, R., Saito, T., Fujimoto, T., Higaki, S., Takahashi, Y., Arai, K., and Yamaha, E. Generation of germ-line chimera zebrafish using primordial germ cells isolated from cultured blastomeres and cryopreserved embryoids. Int. J. Dev. Biol. 54, 1493–1501. (IF 2010 = 2.856) (2010).
  • Saito, T., Goto-Kazeto, R., Fujimoto, T., Kawakami, Y., Arai, K., and Yamaha, E. Inter-species transplantation and migration of primordial germ cells in cyprinid fish. Int. J. Dev. Biol. 54, 1479–1484. (IF 2010 = 2.856) (2010).
  • Yamaha, E., Goto-Kazeto, R., Saito, T., Kawakami, Y., Fujimoto, T., Adachi, S., and Arai, K. Primordial germ cell in teleost fish with special references to its specification and migration. Journal of Applied Ichthyology 26, 816–822. (IF 2010 = 0.945) (2010).
  • Wang, D.S., Zhou, L.Y., Kobayashi, T., Matsuda, M., Shibata, Y., Sakai, F. and Nagahama, Y. Doublesex- and Mab-3-Related Transcription Factor-1 repression of aromatase transcription, a possible mechanism favoring the male pathway in tilapia. Endocrinology 151: 1331-1340 (2010).
  • 三浦 猛 魚粉代替飼料減量としてのイエバエ幼虫とサナギの有効性 (2010).
  • 三浦 猛 “嫌われ者”オニヒトデの意外な利用法 (2010).
  • 若林良和* カツオの国モルディブ.田中雅一ら編:南アジア社会を学ぶ人のために,世界思想社, (2010).


  • Yoshikawa, H., Morishima, K., Fujimoto, T., Saito, T., Kobayashi, T., Yamaha, E., and Arai, K. Chromosome Doubling in Early Spermatogonia Produces Diploid Spermatozoa in a Natural Clonal Fish. Biology of Reproduction 80, 973–979. (IF 2009 = 3.300) (2009).
  • Kobayashi, Y., Nakamura, M., Sunobe, T., Usami, T., Kobayashi, T., Manabe, H., Paul-Prasanth, B., Suzuki, N. and Nagahama, Y. Sex-change in the gobiid fish is mediated through rapid switching of gonadotropin receptors from ovarian to testicular portion or vice-versa. Endocrinology 150: 1503-1511 (2009).
  • Nozaki, M., Miura, C., Tozawa, Y. and Miura, T. The contribution of endogenous cellulase to cellulose digestion in the gut of earthworm. Soil Biol. Biochem. 41: 767-769 (2009).
  • Miura, C., Ohta, T., Ozaki, Y., Tanaka, H. and Miura, T. Trypsin is a multifunctional factor in spermatogenesis. Proc. Natl. Acad. Sci. USA 106: 20972-20877 (2009).
  • Yamaguchi, S., Miura C., Kikuchi, K., Celino, F. T., Agusa, T., Tanabe, S. and Miura, T. Zinc is an essential trace element for spermatogenesis. Proc. Natl. Acad. Sci. USA 106: 10859-10864 (2009).
  • 若林良和* カツオと日本社会 -カツオと海と人の関わりを問い直す-(筑波書房ブックレット42).筑波書房,全71頁 (2009).
  • 若林良和* “ぎょしょく教育”で地域を丸ごと理解する. (2009).


  • Saito, T., Goto-Kazeto, R., Arai, K., and Yamaha, E. Xenogenesis in teleost fish through generation of germ-line chimeras by single primordial germ cell transplantation. Biology of Reproduction 78, 159–166. (IF 2008 = 3.469) (2008).
  • Mita, M., Yoshikuni, M., Ohno, K., Shibata, Y., Paul-Prasanth, B., Pitchayawasin, S., Isobe, M. and Nagahama, Y. A relaxin-like peptide purified from radial nerves induces oocyte maturation and ovulation in the starfish, Asterina pectinifera. Proc. Natl. Acad. Sci. USA 106: 9507-9512 (2008).
  • Nagahama, Y. and Yamashita, M. Regulation of oocyte maturation in fish. Dev. Growth Differ. 50 Suppl 1:S195-219 (2008).
  • 若林良和編著 ぎょしょく教育 愛媛県愛南町発水産版食育の実践と提言. (2008).


  • Yamaha, E., Saito, T., Goto-Kazeto, R., and Arai, K. Developmental biotechnology for aquaculture, with special reference to surrogate production in teleost fishes. Journal of Sea Research 58, 8–22. (IF 2007 = 2.204) (2007).
  • Wang, D.S., Kobayashi, T., Zhou, L.Y., Paul-Prasanth, B., Ijiri, S., Sakai, F., Okubo, K., Morohashi, K. and Nagahama, Y. Foxl2 up-regulates aromatase gene transcription female-specifically by binding to the promoter as well as interacting with Ad4BP/SF-1. Mol. Endocrinol. 21: 712-725 (2007).
  • Matsuda, M., Shinomiya, S., Kinoshita, M., Suzuki, A., Kobayashi, T., Paul-Prasanth, B., Lau, E.L., Hamaguchi, S., Sakaizumi, M. and Nagahama, Y. DMY induces male development in XX medaka fish. Proc. Natl. Acad. Sci. USA 104: 3865-3870 (2007).


  • Miyake, A., Saito, T., Kashiwagi, T., Ando, D., Yamamoto, A., Suzuki, T., Nakatsuji, N., and Nakatsuji, T. Cloning and pattern of expression of the shiro-uo vasa gene during embryogenesis and its roles in PGC development. Int. J. Dev. Biol. 50, 619–625. (IF 2006 = 3.577) (2006).
  • Saito, T., Fujimoto, T., Maegawa, S., Inoue, K., Tanaka, M., Arai, K., and Yamaha, E. Visualization of primordial germ cells in vivo using GFP-nos1 3’UTR mRNA. Int. J. Dev. Biol. 50, 691–699. (IF 2006 = 3.577) (2006).
  • Murakami, M., Ikeda, T., Saito, T., Ogawa, K., Nishino, Y., Nakaya, K., and Funaba, M. Transcriptional regulation of plasminogen activator inhibitor-1 by transforming growth factor-β, activin A and microphthalmia-associated transcription factor. Cellular Signalling 18, 256–265. (IF 2006 = 4.887) (2006).
  • Fujimoto, T., Kataoka, T., Sakao, S., Saito, T., Yamaha, E., and Arai, K. Developmental stages and germ cell lineage of the loach (Misgurnus anguillicaudatus). Zool. Sci. 23, 977–989. (IF 2006 = 1.204) (2006).


  • Nagai, T., Otani, S., Saito, T., Maegawa, S., Inoue, K., Arai, K., and Yamaha, E. Germ-line chimera produced by blastoderm transplantation in zebrafish. Nippon Suisan Gakkaishi 71, 1–9. (IF 2006 = 0.176) (2005).
  • Otani, S., Kitauchi, T., Saito, T., Sakao, S., Maegawa, S., Inoue, K., Arai, K., and Yamaha, E. The formation of primordial germ cells from germline cells in spherical embryos derived from the blastodisc of 2-cell embryos in goldfish, Carassius auratus. Int. J. Dev. Biol. 49, 843–850. (IF 2006 = 3.577) (2005).


  • Fujimoto, T., Kataoka, T., Otani, S., Saito, T., Aita, T., Yamaha, E., and Arai, K. Embryonic stages from cleavage to gastrula in the loach Misgurnus anguillicaudatus. Zool. Sci. 21, 747–755. (IF 2006 = 1.204) (2004).
  • Saito, T., Otani, S., Fujimoto, T., Suzuki, T., Nakatsuji, T., Arai, K., and Yamaha, E. The germ line lineage in ukigori, Gymnogobius species (Teleostei: Gobiidae) during embryonic development. Int. J. Dev. Biol. 48, 1079–1085. (IF 2006 = 3.577) (2004).
  • Tokumoto, T., Tokumoto, M., Horiguchi, R., Ishikawa, K. and Nagahama, Y. Diethylstilbestrol induces fish oocyte maturation. Proc. Natl. Acad. Sci. USA 101: 3686-3690 (2004).


  • Saito, T., Otani, S., Nagai, T., Nakatsuji, T., Arai, K., and Yamaha, E. Germ cell lineage from a single blastomere at 8-cell stage in shiro-uo (ice goby). Zool. Sci. 19, 1027–1032. (IF 2006 = 1.204) (2002).
  • Devlin, R.H. and Nagahama, Y. Sex determination and sex differentiation in fish. Aquaculture 208: 191-366 (2002).
  • Matsuda, M., Nagahama, Y.**, Shinomiya, A., Sato, T., Matsuda, C., Kobayashi, T., Morrey, C.E., Shibata, N., Asakawa, S., Shimizu, N., Hori, H., Hamaguchi, S. and Sakaizumi, M. DMY is a Y-specific DM-domain gene required for male development in the medaka fish. Nature 417: 559-563 **Corresponding author. (2002).


  • Saito, T., Kamimoto, M., Miyake, A., Yamaha, E., Suzuki, T., Nakatsuji, N., and Nakatsuji, T. Mesoderm formation by isolated and cultivated 8-cell stage blastomeres of the teleost, Leucopsarion ptersii (shiro-uo). Int. J. Dev. Biol. 45, 661–668. (IF 2006 = 3.577) (2001).
  • Tanaka, M., Kinosita, M. and Nagahama, Y. (2001). Establishment of medaka (Oryzias latipes) transgenic lines with the expression of GFP fluorescence exclusively in germline cells: a useful model to monitor germline cells in a live vertebrate. Proc. Natl. Acad. Sci. USA 98: 2544-2549 (2001).


  • Guan, G., Todo, T., Tanaka, M., Young, G. and Nagahama, Y. Isoleucine-15 of rainbow trout carbonyl reductase-like 20β-hydroxysteroid dehydrogenase is critical for coenzyme (NADPH) binding. Proc. Natl. Acad. Sci. USA 97: 3079-3083 (2000).


  • Tokumoto, T., Yamashita, M., Tokumoto, M., Katsu, Y. Kajiura, H. and Nagahama, Y. Initiation of cyclin B degradation by the 26S proteasome upon egg activation. J. Cell Biol. 22: 1313-1322 (1997).


  • Yamashita, M., Kajiura, H., Tanaka, T., Onoe, S. and Nagahama, Y. Molecular mechanisms of the activation of maturation-promoting factor during goldfish oocyte maturation. Dev. Biol. 168: 62-75 (1995).


  • Miura, T., Yamauchi, K., Takahashi, H. and Nagahama, Y. Hormonal induction of all stages of spermatogenesis in vitro in the male Japanese eel (Anguilla japonica). Proc. Natl. Acad. Sci. USA 88: 5774-5778 (1991).


  • Yoshikuni, M., Ishikawa, K., Isobe, M., Goto, T. and Nagahama, Y. Characterization of 1-methyladenine binding in starfish oocyte cortices. Proc. Natl. Acad. Sci. USA 85: 1708-1711 (1988).
  • Suzuki, K., Kawauchi, H. and Nagahama, Y. Isolation and characterization of two distinct gonadotropins from chum salmon pituitary glands. Gen. Comp. Endocrinol. 71: 292-301 (1988).


  • Nagahama, Y. and Adachi, S. Identification of a maturation-inducing steroid in a teleost, the amago salmon (Oncorhynchus rhodurus). Dev. Biol. 109: 428-435 (1985).


  • Nagahama, Y. The functional morphology of teleost gonads. In “Fish Physiology” (W.S. Hoar, D.J. Randall and E.M. Donaldson, eds.), Vol. IXA, pp. 223-275. Academic Press, New York (1983).